ECP relatively safe and efficacious for abortion

[guest]

There are very few academicians who will consider using ECP because of the risks of adverse side effects. When used properly for the correct clients, however it can be relatively safe and efficacious. The best article on this is Bowen, Olson et al. JAVMA, 1985;186:783-788.

http://www.vetmed.lsu.edu/eiltslotus/th ... /javma.htm


The dose 44 ug/kg IM given once during estrus to be the best dose (0.02 mg/lb)

It is not effective if used in proestrus or in diestrus, therefore it is essential that the vaginal cytology be examined.

It can induce pyometra if given during diestrus, so be sure the bitch has not entered diestrus when administered.

Other side effects

The bitch will show continued estrous signs, because of the estrogen. It is important that the bitch not be allowed to breed again.

Cystic endometrial hyperplasia can also result after ECP administration.

Bone marrow suppression can be dose related or non-dose related. To avoid dose related, do not give a second injection. Non-dose related bone marrow suppression can be totally avoided only by never giving ECP injections.

Pyometra

No pyometras were seen when the ECP was given during estrus.

Treatment failure

The treatment was 100% efficacious when administered during estrus. side effects and no failures when given during estrus.

Summary: If puppies are wanted it the future and the client is aware that there is a risk and they are willing to take it, then ECP offers an inexpensive, efficacious, relatively safe mismate protocol. However, if the bitch is a valuable breeding bitch, or a surrogate child, then other alternatives may be more attractive to both client and veterinarian.

[Guest]

That is such a load of bull. ECP is dangerous and should never be used.... I worked at a practice that used the stuff like it was water and I saw so many dogs come back with pyos (and several die) it's not even funny........ Bottom line, too many dogs get your dog spayed and you will not have to worry about unwanted pregnancies