sarcoma at site of microchip

evidence-based cancer treatment — the discipline that insists on proof that time-honored medical practices and procedures are actually effective.
No ancedotal stuff please.
Pet cancer treatment can cost ten thousand USA dollars. This forum is for people to tell us how they were able to obtain cancer treatment when they had no pet health insurance to cover the cost. Rabie Vaccine caused cancer often is paid for by the company that produced the vaccine even when not legally required to do so.

sarcoma at site of microchip

Postby malernee » Fri Sep 08, 2006 6:35 pm

Fibrosarcoma with typical features of postinjection sarcoma at site of microchip implant in a dog: histologic and immunohistochemical study
Vet Pathol. July 2006;43(4):545-8.

M Vascellari, E Melchiotti, F Mutinelli
Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Università 10, 35020 Legnaro (PD) (Italy). mvascellari@izsvenezie.it.

Abstract
A 9-year-old, male French Bulldog was examined for a subcutaneous mass located at the site of a microchip implant. Cytologic examination of the mass was suggestive of a malignant mesenchymal neoplasm. Histologically, the mass was confirmed as a high-grade infiltrative fibrosarcoma, with multifocal necrosis and peripheral lymphoid aggregates. By immunohistochemistry, the sample was investigated for vimentin, smooth-muscle actin (SMA), CD3, CD79alpha, and CD18. All the neoplastic cells were positive for vimentin. Scattered cells at the periphery of the lesion were also positive for SMA, highlighting a myofibroblastic phenotype. The lymphoid cells were positive for CD18 and CD3. No aluminum deposits were detected by the aurintricarboxylic acid method. A diagnosis of fibrosarcoma morphologically similar to feline postinjection sarcomas was made. Fibrosarcomas at the site of injections have been reported in dogs and ferrets. Furthermore, neoplastic growth at the site of microchip implant in dog and laboratory rodents has been described.
malernee
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